Major Peptide Resources

Here we provide links to all the web servers/tools which are developed for peptides with special emphasis on therapeutic peptides. This will help researchers to find a tool which will be relevant to their area of peptide research.

Peptide Prediction Servers

AntiCPA web server for designing and discovering novel anticancer peptides.
ToxinPredInsilico approach for predicting toxicity of peptides and proteins.
AntiBP2Server for antibacterial peptide prediction.
ClassAMPA prediction tool for classification of AMPs.
FoldAmyloidServer for prediction of amyloidogenic regions in the protein chain.
TumorHPDServer for designing of tumor homing peptides.
HLPA web server for predicting half-life of peptides in intestine like environment
CellPPDServer for designing of cell penetrating peptides.
SignalP 4.1Server for predicting the presence and location of signal peptide cleavage sites in amino acid sequences from different organisms: Gram-positive prokaryotes, Gram-negative prokaryotes, and eukaryotes.
PrediSiSoftware tool for predicting signal peptide sequences and their cleavage positions in bacterial and eukaryotic proteins
HemoPIA Server for prediction of hemolytic potency of peptides.
AntiAngioPredA Server for prediction and designing of antiangiogenic peptides.
ChloroP 1.1The ChloroP server predicts the presence of chloroplast transit peptides (cTP) in protein sequences and the location of potential cTP cleavage sites.
PEPstrA Server for prediction of tertiary structure prediction of peptides.
PEPstrMODStructure prediction of peptides containing natural, non-natural and modified residues.
PEP-FOLDA de novo approach for predicting peptide structures from amino acid sequences.
Antigenic Peptide PredictionA de novo This program predicts those segments from within a protein sequence that are likely to be antigenic by eliciting an antibody response..
PEP2DA web server for predicting secondary structure of peptides.
ProPredMHC Class-II binding peptide prediction server.
MHC2PredSVM based method for prediction of promiscuous MHC Class II binders
QSPpredServer for predicting quorum sensing peptides
IL4predIn silico platform for designing and disovering of interleukin-4 inducing peptides.
dPABBsA server for predicting and designing biofilm active peptides.
IFNepitopeA server for predicting and designing interferon-gamma inducing peptides.

Peptide Databases

S.No.Database NameDescription
BIOPEPBIOPEP database and other programs for processing bioactive peptide sequences
Brainpepsblood-brain barrier properties of peptides
CAMPCollection of sequences and structures of antimicrobial peptides
CPPsiteA curated database of cell penetrating peptides
EROP-MoscowThe EROP-Moscow oligopeptide database
MilkAMPa comprehensive database of antimicrobial peptides of dairy origin
RAPDRecombinantly-produced Antimicrobial Peptides Database
TumorHoPeA Database of Tumor Homing Peptides
HemolytikDatabase of hemolytic peptides
SPdba signal peptide resource
Quorumpepschemical space, microbial origin and functionality of quorum sensing peptides
YADAMPAnti-microbial Database
PeptideDBBioactive peptide database in Metazoa
IEDBImmune Epitope Database
SYFPEITHIdatabase for MHC ligands and peptide motifs
MHCBN 4.0MHC binding and non-binding peptides
AntiJenquantitative binding data for peptides binding to MHC Ligand, TCR-MHC Complexes, T Cell Epitope, TAP, B Cell Epitope molecules and immunological Protein-Protein interactions
BcipepDatabase of B-cell epitopes
ACEpepDBFood derived antihypertensive peptides
Human Urine Peptide DatabaseA database of naturally occurring human urinary peptides and proteins for use in clinical applications
PepBankpeptides based on sequence text mining and public peptide data sources.
PhytAMPdatabase dedicated to antimicrobial plant peptides
EPIMHCa curated database of MHC-binding peptides for customized computational vaccinology.
Parapeprepository of experimentally validated anti-parasitic peptides
CancerPPDDatabase of Anticancer peptides and proteins
PEPlifeA database of half life of peptides
DADPDatabase of Anuran Defense Peptides
DAMPDDragon Antimicrobial Peptide Database
APD2The Antimicrobial Peptide Database
AMPerA Database and an Automated Discovery Tool for Gene-Coded Antimicrobial Peptides
DEFENSINS Knowledgebasemanually curated database and information source devoted to the defensin family of antimicrobial peptides
NeuroPepA comprehensive resource of Neuropeptides
NeuroPedianeuropeptide database and spectral library.
MPID-T2MHC-Peptide Interaction Database-TR version 2
Signal Peptide websiteAn Information Platform for Signal Sequences and Signal Peptides
SwePepDatabase designed for endogenous peptides and mass spectrometry
AVPdbdatabase of experimentally validated antiviral peptides
PeptaibolPeptaibols generally exhibit antimicrobial activity and are referred to as antibiotic peptides
PEPTIDOME DBa comprehensive fact-database for endogenous peptides
NORINEa database of nonribosomal peptides
ConoServera database for conopeptides which are peptides expressed by carnivorous marine cone snails
BaAMPsBiofilm-active AMPs database: antimicrobial peptides (AMPs) specifically tested against microbial biofilms.
BACTIBASEdata repository of bacteriocin natural antimicrobial peptides
LAMPA database linking antimicrobial peptide.
DBAASPDatabase of Antimicrobial Activity and Structure of Peptides
HIPdbA Database of Experimentally Validated HIV Inhibiting Peptides
HMRBaseA database of hormones and their receptors
BactPepDBa database of predicted peptides from a exhaustive survey of complete prokaryote genomes
Transitpeppeptides are responsible for the transport of a protein encoded by a nuclear gene to a particular organell
Arabidopsis Unannotated Secreted Peptide DatabaseThis is a searchable database of bioinformatic predictions of putative intergenic unannotated secreted peptides from Arabidopsis thaliana.
MHCPEPdatabase of MHC-binding peptides.
JenPepdatabase of quantitative functional peptide data for immunology
PenBasethe shrimp antimicrobial peptide penaeidin database
database of circulating human peptidesComposition of the peptide fraction in human blood plasma: database of circulating human peptides
Database of biologically active peptide sequencesDatabase of biologically active peptide sequences
MPIDMHC-Peptide Interaction Database for sequence-structure-function information on peptides binding to MHC molecules
SAPDSynthetic Antibiotic Peptides Database
CoPSComprehensive Peptide Signature Database
XMAna Homo sapiens mutated-peptide database for the MS analysis of cancerous cell states.
MycosecA database for signal peptide bearing genes of mycobacterium
ANTIMICa database of antimicrobial sequences
AMSdbAntimicrobial sequences database
BIOPDa web-based information center for bioactive peptides