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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 21 are 161
Results from 100 - 125

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SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM2381	CUUCUUCGUCGAGACCAUGTY CAUGGUCUCGACGAAGAAGTY	Glucosamine analogue Glucosamine analogue	21 21	Base Base	53 percent target mRNA inhibition	23743279
SM2387	CUUCUUCGUCGAGACCAUGTX CAUGGUCUCGACGAAGAAGTX	Thymidine analogue Thymidine analogue	21 21	Base Base	83 percent target mRNA inhibition	23743279
SM2388	CUUCUUCGUCGAGACCAUGTY CAUGGUCUCGACGAAGAAGTY	Glucosamine analogue Glucosamine analogue	21 21	Base Base	68 percent target mRNA inhibition	23743279
SM2465	CGGAGGCUGGGAUGCCUUUTT AAAGGCAUCCCAGCCUCCGTT	Assymetric siRNA (3-End Overhang) Assymetric siRNA (3-End Overhang)	21 1	NA NA	60 percent target mRNA inhibition	23135004
SM2659	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Peptide nucleic acids 0	21 0	Phosphate 0	82 percent target mRNA inhibition	19325750
SM2661	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Peptide nucleic acids Peptide nucleic acids	21 21	Phosphate Phosphate	81 percent target mRNA inhibition	19325750
SM2663	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Peptide nucleic acids 0	21 0	Phosphate 0	80 percent target mRNA inhibition	19325750
SM2665	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Peptide nucleic acids Peptide nucleic acids	21 21	Phosphate Phosphate	75 percent target mRNA inhibition	19325750
SM2667	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Peptide nucleic acids 0	21 0	Phosphate 0	80 percent target mRNA inhibition	19325750
SM2669	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Peptide nucleic acids Peptide nucleic acids	21 21	Phosphate Phosphate	80 percent target mRNA inhibition	19325750
SM2671	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Peptide nucleic acids 0	21 0	Phosphate 0	70 percent target mRNA inhibition	19325750
SM2673	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Peptide nucleic acids Peptide nucleic acids	21 21	Phosphate Phosphate	56 percent target mRNA inhibition	19325750
SM2688	UUCUCCGAACGUGUCACGUUUU ACGUGACACGUUCGGAGAAUUU	UnLocked nucleic acid Unlocked nucleic acid* Locked nucleic acid	21 6 * 20,21	Sugar Sugar	2.75 (log-10 CVB-3 titre pfu/ml)	20005874
SM2689	UUCUCCGAACGUGUCACGUUUU ACGUGACACGUUCGGAGAAUUU	UnLocked nucleic acid Unlocked nucleic acid* Locked nucleic acid	21 7 * 20,21	Sugar Sugar	2.625 (log-10 CVB-3 titre pfu/ml)	20005874
SM2690	UUCUCCGAACGUGUCACGUUUU ACGUGACACGUUCGGAGAAUUU	UnLocked nucleic acid Locked nucleic acid	21 20,21	Sugar Sugar	2.93 (log-10 CVB-3 titre pfu/ml)	20005874
SM2694	UUCUCCGAACGUGUCACGUUUU ACGUGACACGUUCGGAGAAUUU	UnLocked nucleic acid 0	21 0	Sugar 0	2.73 (log-10 CVB-3 titre pfu/ml)	20005874
SM2714	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Pyrene modification 0	21 0	Sugar 0	71 percent target mRNA inhibition	20485810
SM2715	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Anthracene 0	21 0	Sugar 0	75 percent target mRNA inhibition	20485810
SM2716	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Naphthalene modification 0	21 0	Sugar 0	69 percent target mRNA inhibition	20485810
SM2717	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Trifluoromethylbenzene 0	21 0	Sugar 0	74 percent target mRNA inhibition	20485810
SM2718	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Fluorobenzene 0	21 0	Sugar 0	70 percent target mRNA inhibition	20485810
SM2719	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Methyl 0	21 0	Sugar 0	70 percent target mRNA inhibition	20485810
SM2749	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Pyrene modification 0	21 0	Sugar 0	80 percent target mRNA inhibition	20485810
SM2750	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Anthracene 0	21 0	Sugar 0	77 percent target mRNA inhibition	20485810
SM2751	UCGAAGUAUUCCGCGUACGTT CGUACGCGGAAUACUUCGATT	Naphthalene modification 0	21 0	Sugar 0	80 percent target mRNA inhibition	20485810



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