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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 17585051 are 28
Results from 0 - 25

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SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM2299	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	Dihydrouridine 0	19 0	Base 0	84 percent target mRNA inhibition	17585051
SM2300	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	Pseudouridine 0	19 0	Base 0	70 percent target mRNA inhibition	17585051
SM2301	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	2-Thiouridine 0	19 0	Base 0	76 percent target mRNA inhibition	17585051
SM2302	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	0 Dihydrouridine	0 19	0 Base	61 percent target mRNA inhibition	17585051
SM2303	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	0 Pseudouridine	0 19	0 Base	86 percent target mRNA inhibition	17585051
SM2304	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	0 2-Thiouridine	0 19	0 Base	91 percent target mRNA inhibition	17585051
SM2305	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	0 Dihydrouridine	0 10	0 Base	60 percent target mRNA inhibition	17585051
SM2306	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	0 Pseudouridine	0 10	0 Base	69 percent target mRNA inhibition	17585051
SM2307	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	0 2-Thiouridine	0 10	0 Base	86 percent target mRNA inhibition	17585051
SM2308	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	0 Wobble Base Pair	0 9	0 Base	60 percent target mRNA inhibition	17585051
SM2309	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	0 Wobble Base Pair* 2-Thiouridine	0 9 * 10	0 Base	81 percent target mRNA inhibition	17585051
SM2310	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	Dihydrouridine Pseudouridine	19 19	Base Base	90 percent target mRNA inhibition	17585051
SM2311	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	Dihydrouridine 2-Thiouridine	19 19	Base Base	92 percent target mRNA inhibition	17585051
SM2312	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	Dihydrouridine Pseudouridine	19 10	Base Base	89 percent target mRNA inhibition	17585051
SM2313	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	Dihydrouridine 2-Thiouridine	19 10	Base Base	87 percent target mRNA inhibition	17585051
SM2317	ACAUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	0 2-Thiouridine	0 4,7,10,13,14,17,19	0 Base	89 percent target mRNA inhibition	17585051
SM2318	AUGAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	0 2-Thiouridine	0 4,7,10,13,17,19	0 Base	88 percent target mRNA inhibition	17585051
SM2319	GAAGCAGCACGACUUTT AAGUCGUGCUGCUUCAUGUTT	0 2-Thiouridine	0 4,7,10,13,14	0 Base	20 percent target mRNA inhibition	17585051
SM2321	AGCUUUGUGGAGAUGGUGGTT CCACCAUCUCCACAAAGCUTT	0 Wobble Base Pair	0 8	0 Base	29 percent target mRNA inhibition	17585051
SM2322	AGCUUUGUGGAGAUGGUGGTT CCACCAUCUCCACAAAGCUTT	0 Wobble Base Pair* 2-Thiouridine	0 8 * 9	0 Base	67 percent target mRNA inhibition	17585051
SM2324	AUACAGGCAGCAGUAACUUUTT AAAGUUACUGCUGCCUGUAUTT	0 2-Thiouridine	0 20	0 Base	72 percent target mRNA inhibition	17585051
SM2325	AUACAGGCAGCAGUAACUUUTT AAAGUUACUGCUGCCUGUAUTT	Dihydrouridine 0	20 0	Base 0	71 percent target mRNA inhibition	17585051
SM2326	AUACAGGCAGCAGUAACUUUTT AAAGUUACUGCUGCCUGUAUTT	0 2-Thiouridine	0 18, 20	0 Base	76 percent target mRNA inhibition	17585051
SM2327	AGCUUUGUGGAGAUGGUGGTT AAAGUUACUGCUGCCUGUAUTT	Pseudouridine* Dihydrouridine 0	2 * 20 0	Base 0	82 percent target mRNA inhibition	17585051
SM2328	AUACAGGCAGCAGUAACUUUTT AAAGUUACUGCUGCCUGUAUTT	Dihydrouridine Pseudouridine	20 20	Base Base	77 percent target mRNA inhibition	17585051



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