A database of FDA approved therapeutic peptides and proteins
ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1028 | Th1005 | Etanercept | LPAQVAFTPYAPEPGSTCRL Full view | 255 | IIa | Immunological | Enbrel | Immunex Corp | Lyophilized powder. | Subcutaneous injection | Immunosuppressive Agents | Tumor necrosis factor,Tumor necrosis factor receptor superfamily member 1B,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c,Lymphotoxin-alpha,Low affinity immunoglobulin gamma Fc region re |
1029 | Th1005 | Etanercept | LPAQVAFTPYAPEPGSTCRL Full view | 255 | IIa | Immunological | Enbrel Sureclick | N.A. | Solution | Subcutaneous injection | Immunosuppressive Agents | Tumor necrosis factor,Tumor necrosis factor receptor superfamily member 1B,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c,Lymphotoxin-alpha,Low affinity immunoglobulin gamma Fc region re |
1049 | Th1008 | Peginterferon alfa-2a | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Pegasys | Hoffman-La Roche Inc | Sterile, preservative-free, colorless to light yellow injectable solution | Subcutaneous Injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1110 | Th1015 | Interferon alfa-n3 | Alpha-2A:CDLPQTHSLG< Full view | 235 | Ib | Immunological | Alferon | Interferon Sciences Inc. | Solution | Injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1111 | Th1015 | Interferon alfa-n3 | Alpha-2A:CDLPQTHSLG< Full view | 235 | Ib | Immunological | Alferon LDO | N.A. | N.A. | N.A. | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1112 | Th1015 | Interferon alfa-n3 | Alpha-2A:CDLPQTHSLG< Full view | 235 | Ib | Immunological | Alferon N Injection | N.A. | N.A. | N.A. | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1117 | Th1016 | Pegfilgrastim | MTPLGPASSLPQSFLLKCLE Full view | 175 | Ib | Immunological | Neulasta | Amgen Inc. | Solution | Subcutaneous injection | Immunosuppressive Agents, Anti-neutropenic agents | Granulocyte colony-stimulating factor receptor,Neutrophil elastase |
1120 | Th1017 | Sargramostim | APARSPSPSTQPWEHVNAIQ Full view | 127 | Ib | Immunological | Leucomax | Novartis | Solution | Subcutaneous and Intravenous infusion | Immunosuppressive Agents | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan |
1121 | Th1017 | Sargramostim | APARSPSPSTQPWEHVNAIQ Full view | 127 | Ib | Immunological | Leukine | Berlex Laboratories Inc | Sterile, preserved (1.1% benzyl alcohol), injectable solution (500 mcg/mL) and also as sterile, white, preservative free lyophilized powder (250 mcg) that requires reconstitution with 1 mL sterile water for Injection | Subcutaneous Injection (SC) or Intravenous infusion (IV) | Immunosuppressive Agents | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan |
1135 | Th1019 | Peginterferon alfa-2b | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | PEG-Intron | Schering Corp | Powder | Subcutaneous injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1136 | Th1019 | Peginterferon alfa-2b | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Unitron PEG | N.A. | Lyophilized powder | Subcutaneous injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1180 | Th1023 | Anakinra | MRPSGRKSSKMQAFRIWDVN Full view | 153 | IIa | Immunological | Kineret | Amgen Inc | Sterile, clear, colorless-to-white, preservative free solution | Subcutaneous (SC) administration | Immunosuppressive Agents, Anti-rheumatic agents | Interleukin-1 receptor type 1 |
1193 | Th1025 | Intravenous Immunoglobulin | IGG1:PSALTQPPSASGSLG Full view | 250 | Ia | Immunological | Civacir | N.A. | N.A. | N.A. | Immunosuppressive Agents, Immunologic factors, Anti-infective agents | High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg |
1194 | Th1025 | Intravenous Immunoglobulin | IGG1:PSALTQPPSASGSLG Full view | 250 | Ia | Immunological | Flebogamma | Instituto Grifols SA | Sterile, clear or slightly opalescent and colorless to pale yellow, liquid | Intravenous infusion | Immunosuppressive Agents, Immunologic factors, Anti-infective agents | High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg |
1195 | Th1025 | Intravenous Immunoglobulin | IGG1:PSALTQPPSASGSLG Full view | 250 | Ia | Immunological | Gamunex | Talecris Biotherapeutics | Sterile solution | Intravenous infusion | Immunosuppressive Agents, Immunologic factors, Anti-infective agents | High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg |
1226 | Th1030 | Interferon gamma-1b | CYCQDPYVKEAENLKKYFNA Full view | 146 | Ib | Immunological | Actimmune | InterMune Inc | Sterile, clear, colorless solution | Subcutaneous Injection | Immunosuppressive Agents | Interferon gamma receptor 1,Interferon gamma receptor 2 |
1316 | Th1044 | Adalimumab | Light-chain:DIQMTQS< Full view | 230 | Ic | Immunological | Humira | Abbott Laboratories | Sterile, preservative-free solution | Subcutaneous administration | Immunosuppressive Agents, Anti-inflammatory, Antirheumatic agents | Tumor necrosis factor,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamm |
1317 | Th1044 | Adalimumab | Light-chain:DIQMTQS< Full view | 230 | Ic | Osteological | Humira Pen | Abbott Laboratories | Sterile, preservative-free solution | Subcutaneous injection | Immunosuppressive Agents, Anti-inflammatory, Antirheumatic agents | Tumor necrosis factor,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamm |
1341 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Avonex | Biogen Inc | Lyophilized powder vial, Sterile liquid as single used prefilled syringe and also available as single use prefilled autoinjector. | Intramuscular Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1342 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Betaferon | Bayer | Powder and solvent that are made upto make solution. | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1343 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Betaseron | Merck | Sterile, white to off-white powder | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1344 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Blastoferon | Sidus | N.A. | N.A. | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1345 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Extavia | Novartis | Sterile, white to off-white powder | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1346 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Rebif | Merck | Sterile solution in a prefilled syringe or REBIF Rebidose autoinjector | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1368 | Th1054 | Infliximab | N.A. Full view | 0 | IIa | Immunological | REMICADE | Centocor Inc | Sterile, white, lyophilized powder, following reconstitution with 10 mL of Sterile Water for Injection, USP, the resulting pH is approximately 7.2. | Intravenous infusion | Antirheumatic Agents, Anti-Inflammatory Agents, Non-Steroidal, Dermatologic Agents, Gastrointestinal Agents and Immunosuppressive Agents | Tumor necrosis factor |
1376 | Th1057 | Interferon beta-1b | MSYNLLGFLQRSSNFQSQKL Full view | 166 | Ib | Immunological | Betaseron | Bayer | Sterile, white to off-white powder | Subcutaneous Injection | Adjuvants, Immunologic and Immunosuppressive Agents | N.A. |
1377 | Th1057 | Interferon beta-1b | MSYNLLGFLQRSSNFQSQKL Full view | 166 | Ib | Immunological | Betaferon | Bayer | Powder and solvent that are made upto make solution. | Subcutaneous Injection | Adjuvants, Immunologic and Immunosuppressive Agents | N.A. |
1378 | Th1057 | Interferon beta-1b | MSYNLLGFLQRSSNFQSQKL Full view | 166 | Ib | Immunological | Extavia | Novartis | Sterile, white to off-white powder | Subcutaneous Injection | Adjuvants, Immunologic and Immunosuppressive Agents | N.A. |
1379 | Th1058 | Interferon alfacon-1 | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological/Infectious | INFERGEN | Kadmon Pharmaceuticals, LLC. | Sterile, clear, colorless, preservative-free liquid | Subcutaneous Injection | Antiviral Agents and Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1398 | Th1063 | Basiliximab | Heavy Chain: QLQQSGT Full view | 657 | IIa | Immunological | Simulect | Novartis | Sterile lyophilisate which is available in 6 mL colorless glass vials and is available in 10 mg and 20 mg strength | intravenous infusion mainly or bolus (if no allergic reactions occurs) | Immunosuppressive Agents | N.A. |
1400 | Th1064 | Muromonab | Heavy Chain: QVQLQQS Full view | 664 | IIa | Immunological | ORTHOCLONE OKT3 STERILE SOLUTION | Centocor Ortho Biotech, L.P. | Sterile Solution is a murine monoclonal antibody to the CD3 antigen of human T cells which functions as an immunosuppressant. | For Intravenous Use Only | Immunologic Factors and Immunosuppressive Agents | N.A. |
1442 | Th1078 | Efalizumab | Light Chain:DIQMTQSP Full view | 229 | IIa | Immunological | RAPTIVA | Genentech, Inc. | Sterile, white to off-white, lyophilized powder in single-use glass vials | Subcutaneous injection. | Immunosuppressive Agents | Iduronic acid |
1449 | Th1081 | Antithymocyte Globulin | N.A. Full view | 0 | IIa | Immunological | Antithymocyte globulin | Pfizer | N.A. | Intravenous infusion | Immunologic Factors and Immunosuppressive Agents | N.A. |
1451 | Th1082 | Filgrastim | MTPLGPASSLPQSFLLKCLE Full view | 175 | Ib | Immunological | N.A. | N.A. | N.A. | N.A. | Immunosuppressive Agents, Antineutropenic Agents and Hematopoietic Agents | Lutropin-choriogonadotropic hormone receptor,Follicle-stimulating hormone receptor |
1456 | Th1086 | Interferon Alfa-2B, Recombinant | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | INTRON® A | Merck | Powder or solution | Intramuscular, Subcutaneous, Intralesional, or Intravenous injection | Immunosuppressive Agents | Granulocyte colony-stimulating factor receptor,Neutrophil elastase, Coagulation factor X,Coagulation factor XI,Coagulation factor VII,Coagulation factor VIII,Prothrombin,Prolow-density lipoprotein receptor-related protein 1,Vitamin K-dependent gamma-carboxylase, Platelet-derived growth factor receptor beta,Platelet-derived growth factor receptor alpha,Alpha-2-macroglobulin |
1466 | Th1090 | Daclizumab | QVQLVQSGAEVKKPGSSVKV Full view | 674 | IIa | Immunologicals | Zenapax | Roche | Clear, sterile, colorless concentrate for further dilution and intravenous administration | Intravenous injection | Immunosuppressive Agents | Fusion glycoprotein F0,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c |
1495 | Th1102 | Abatacept | MHVAQPAVVLASSRGIASFV Full view | 357 | IIa | Immunological | ORENCIA | Bristol-Myers Squibb | Lyophilized powder, supplied as a sterile, white, preservative-free, lyophilized powder for intravenous administration | Intravenous infusion and Subcutaneous injection | Antirheumatic Agents and Immunosuppressive Agents | T-lymphocyte activation antigen CD80,T-lymphocyte activation antigen CD86 |
1562 | Th1122 | Rilonacept | rilonacept|Homo sapi Full view | 880 | IIa | Immunological | Arcalyst | Regeneron Pharmaceuticals | Sterile, white to off-white, lyophilized powder | Subcutaneous injection | Immunosuppressive Agents | Interleukin-1 beta,Interleukin-1 alpha,Interleukin-1 receptor antagonist protein |
1596 | Th1126 | Belatacept | MHVAQPAVVLASSRGIASFV Full view | 357 | IIa | Immunological | Nulojix | Bristol-Myers Squibb | Sterile, white or off-white lyophilized powder | Intravenous injection | Antirheumatic Agents and Immunosuppressive Agents | T-lymphocyte activation antigen CD86,T-lymphocyte activation antigen CD80 |
1644 | Th1147 | Natalizumab | N.A. Full view | 0 | IIa | Genetic/Immunological | Tysabri | Biogen Idec Inc. | Sterile, colorless, and clear to slightly opalescent concentrate | Intravenous infusion | Immunosuppressive agents | N.A. |
1708 | Th1170 | Blinatumomab | DIQLTQSPASLAVSLGQRAT Full view | 504 | IIIc | Cancer/Genetic | Blincyto | AMGEN | Lyophilized Powder for intravenous administration | Intravenous | Antineoplastic Agents, Immunosuppressive Agents, Monoclonal antibodies, Antineoplastic and Immunomodulating Agents | B-lymphocyte antigen CD19; T-cell surface glycoprotein CD3 delta chain |
1785 | Th1190 | Immune Globulin Human | IGG1: PSALTQPPSASGSL Full view | 1338 | IIIb | Immunological Disorders | Bivigam | Kedrion Biopharma, Inc. | Injection, Solution | Intravenous | Immunologic Factors; Immunosuppressive Agents; Anti-Infective Agents | High affinity immunoglobulin gamma Fc receptor I; High affinity immunoglobulin gamma Fc receptor IB; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; Complement C3; Complement C4-A; Complement C4-B; Complement C5. |
1786 | Th1190 | Immune Globulin Human | IGG1: PSALTQPPSASGSL Full view | 1338 | IIIb | Immunological Disorders | Bivigam | Biotest Pharmaceuticals Corporation | Injection, Solution | Intravenous | Immunologic Factors; Immunosuppressive Agents; Anti-Infective Agents | High affinity immunoglobulin gamma Fc receptor I; High affinity immunoglobulin gamma Fc receptor IB; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; Complement C3; Complement C4-A; Complement C4-B; Complement C5. |
1788 | Th1190 | Immune Globulin Human | IGG1: PSALTQPPSASGSL Full view | 1338 | IIIb | Immunological Disorders | Carimune Nanofiltered | Csl Behring Ag | Injection, Powder, Lyophilized, for Solution | Intravenous | Immunologic Factors; Immunosuppressive Agents; Anti-Infective Agents | High affinity immunoglobulin gamma Fc receptor I; High affinity immunoglobulin gamma Fc receptor IB; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; Complement C3; Complement C4-A; Complement C4-B; Complement C5. |
1791 | Th1190 | Immune Globulin Human | IGG1: PSALTQPPSASGSL Full view | 1338 | IIIb | Immunological Disorders | Flebogamma Dif | GRIFOLS USA, LLC | Injection, Solution | Intravenous | Immunologic Factors; Immunosuppressive Agents; Anti-Infective Agents | High affinity immunoglobulin gamma Fc receptor I; High affinity immunoglobulin gamma Fc receptor IB; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; Complement C3; Complement C4-A; Complement C4-B; Complement C5. |
1793 | Th1190 | Immune Globulin Human | IGG1: PSALTQPPSASGSL Full view | 1338 | IIIb | Immunological Disorders | Gamastan | Cutter Med & Biol, Division Of Miles Canada Ltd. | liquid | Intramuscular | Immunologic Factors; Immunosuppressive Agents; Anti-Infective Agents | High affinity immunoglobulin gamma Fc receptor I; High affinity immunoglobulin gamma Fc receptor IB; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; Complement C3; Complement C4-A; Complement C4-B; Complement C5. |
1794 | Th1190 | Immune Globulin Human | IGG1: PSALTQPPSASGSL Full view | 1338 | IIIb | Immunological Disorders | Gamastan S/d | GRIFOLS USA, LLC | Injection | Intramuscular | Immunologic Factors; Immunosuppressive Agents; Anti-Infective Agents | High affinity immunoglobulin gamma Fc receptor I; High affinity immunoglobulin gamma Fc receptor IB; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; Complement C3; Complement C4-A; Complement C4-B; Complement C5. |
1795 | Th1190 | Immune Globulin Human | IGG1: PSALTQPPSASGSL Full view | 1338 | IIIb | Immunological Disorders | Hyqvia | Baxalta Us Inc. | Liquid | Intravenous infusion | Immunologic Factors; Immunosuppressive Agents; Anti-Infective Agents | High affinity immunoglobulin gamma Fc receptor I; High affinity immunoglobulin gamma Fc receptor IB; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; Complement C3; Complement C4-A; Complement C4-B; Complement C5. |
1796 | Th1190 | Immune Globulin Human | IGG1: PSALTQPPSASGSL Full view | 1338 | IIIb | Immunological Disorders | Iveegam Immuno 5000mg (iv) | Baxter Ag | NA | NA | Immunologic Factors; Immunosuppressive Agents; Anti-Infective Agents | High affinity immunoglobulin gamma Fc receptor I; High affinity immunoglobulin gamma Fc receptor IB; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; Complement C3; Complement C4-A; Complement C4-B; Complement C5. |
1798 | Th1192 | Ustekinumab | NA Full view | 0 | IIIb | Infectious Disease | Stelara | Janssen Biotech, Inc. | Solution fro Injection | Subcutaneous | Deramtologic agent, Immunosuppressive agent, antineoplastic agent | Interleukin-12 subunit beta |