A database of FDA approved therapeutic peptides and proteins
ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1001 | Th1001 | Lepirudin | LVYTDCTESGQNLCLCEGSN Full view | 65 | Ia | Hematological,Metabolic | Refludan | Berlex Labs | Sterile, white, freeze-dried powder | Intravenous infusion | Antithrombins and Fibrinolytic Agents | Prothrombin |
1022 | Th1003 | Dornase alfa | LKIAAFNIQTFGETKMSNAT Full view | 255 | Ib | Metabolic | Pulmozyme | Genentech Inc | N.A. | Administered by inhalation of an aerosol mist produced by a compressed air driven nebulizer system | Enzymes | DNA |
1023 | Th1003 | Dornase alfa | LKIAAFNIQTFGETKMSNAT Full view | 255 | Ib | Metabolic | Viscozyme | Roche (Chile) | N.A. | Administered by inhalation of an aerosol mist produced by a compressed air driven nebulizer system | Enzymes | DNA |
1032 | Th1006 | Bivalirudin | FPRPGGGGNGDFEEIPEEYL Full view | 20 | Ia | Hematological,Metabolic | Angiomax | Medicines Co or MDCO | White lyophilized cake in single-use vials | Intravenous infusion | Antithrombins | Prothrombin |
1033 | Th1006 | Bivalirudin | FPRPGGGGNGDFEEIPEEYL Full view | 20 | Ia | Hematological,Metabolic | Angiox | The Medicines Company UK Ltd | Powder for concentrate for solution | Injection | Antithrombins | Prothrombin |
1055 | Th1009 | Alteplase | SYQVICRDEKTQMIYQQHQS Full view | 255 | Ib | Hematological,Metabolic | Activase | Genentech Inc | Sterile, white to off-white, lyophilized powder | Intravenous | Thrombolytic Agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1 |
1067 | Th1012 | Reteplase | SYQGNSDCYFGNGSAYRGTH Full view | 255 | Ib | Hematological,Metabolic | Retavase | Centocor | Sterile, white, lyophilized powder | Intravenous Injection | Fibrinolytic Agents, Thrombolytic agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1 |
1148 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Advate | N.A. | Powder form | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1149 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Alphanate | N.A. | Lyophilized powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1150 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Bioclate | Baxter Healthcare Corporation, Hyland Division and Genetics Institute, Inc. | Sterile, nonpyrogenic, off-white to faint yellow, lyophilized powder | Intravenous infusion | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1151 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Helixate FS | N.A. | Sterile, stable, purified, nonpyrogenic, dried concentrate | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1152 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Hemofil M | N.A. | Dry concentrate | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1153 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Hyate:C | N.A. | Powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1154 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Koate-HP | N.A. | Powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1155 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Kogenate FS | N.A. | Powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1156 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Monarc-M | N.A. | Powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1157 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Monoclate-P | N.A. | Lyophilized powder for solution | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1158 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | ReFacto | N.A. | Lyophilized powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1159 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Xyntha | N.A. | Sterile, nonpyrogenic, preservative-free, freeze-dried powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1201 | Th1026 | Anistreplase | SYQVICRDEKTQMIYQQHQS Full view | 255 | Ic | Hematological,Metabolic | Eminase | Wulfing Pharma GmbH | Dry powder | Intravenous infusion | Thrombolytic Agents, Fibrinolytic agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1 |
1210 | Th1028 | Tenecteplase | SYQVICRDEKTQMIYQQHQS Full view | 255 | Ib | Hematological,Metabolic | TNKase | Genentech Inc | Sterile, white to off-white, lyophilized powder | Intravenous Injection | Thrombolytic Agents, Fibrinolytic agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1,Plasminogen activator inhibitor 2,Tetranectin,Keratin, type II cytoskeletal 8,Annexin A2,Calreticulin,Calnexin,Prolow-density lipoprotein |
1234 | Th1032 | Coagulation factor VIIa | ANAFLEELRPGSLERECKEE Full view | 255 | Ib | Hematological,Metabolic | NovoSeven | Novo Nordisk | Sterile, white lyophilized powder | Injection | Thrombotic Agents, Coagulants | Coagulation factor X,Serine protease hepsin,Tissue factor pathway inhibitor,Vitamin K-dependent gamma-carboxylase,Coagulation factor VII,Tissue factor |
1252 | Th1035 | Glucagon recombinant | HSQGTFTSDYSKYLDSRRAQ Full view | 29 | IV | Hormonal/Metabolic/genetic | GlucaGen | Novo Nordisk | Sterile, lyophilized white powder | Subcutaneous, Intramuscular, or Intravenous infusion | Hypoglycemic Agents | Glucagon receptor,Glucagon-like peptide 2 receptor,Glucagon-like peptide 1 receptor |
1253 | Th1035 | Glucagon recombinant | HSQGTFTSDYSKYLDSRRAQ Full view | 29 | IV | Hormonal/Metabolic/genetic | Glucagon | Eli Lilly | Powder | Subcutaneously or Intramuscularly Injection | Hypoglycemic Agents | Glucagon receptor,Glucagon-like peptide 2 receptor,Glucagon-like peptide 1 receptor |
1275 | Th1040 | Insulin Lispro | A chain:GIVEQCCTSICS Full view | 51 | Ia | Hormonal/Metabolic/genetic | Humalog | Eli Lilly | Sterile, aqueous, clear, and colorless solution | Subcutaneous and Intravenous infusion | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1276 | Th1040 | Insulin Lispro | A chain:GIVEQCCTSICS Full view | 51 | Ia | Hormonal/Metabolic/genetic | Humalog KwikPen | Eli Lilly | Solution | Subcutaneous injection | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1277 | Th1040 | Insulin Lispro | A chain:GIVEQCCTSICS Full view | 51 | Ia | Hormonal/Metabolic/genetic | Humalog Pen | Eli Lilly | N.A. | N.A. | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1283 | Th1041 | Insulin Glargine | A-chain:GIVEQCCTSICS Full view | 53 | Ia | Hormonal/Metabolic/genetic | Lantus | Sanofi-Aventis | Solution | Subcutaneous injection | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1284 | Th1041 | Insulin Glargine | A-chain:GIVEQCCTSICS Full view | 53 | Ia | Hormonal/Metabolic/genetic | Lantus OptiSet | N.A. | Solution | Subcutaneous injection | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1285 | Th1041 | Insulin Glargine | A-chain:GIVEQCCTSICS Full view | 53 | Ia | Hormonal/Metabolic/genetic | Lantus SoloStar | N.A. | Solution | Subcutaneous injection | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1305 | Th1043 | Rasburicase | SAVKAARYGKDNVRVYKVHK Full view | 255 | Ic | Metabolic/Genetic | Elitek | Sanofi-Synthelabo Inc | Sterile, white to off-white, lyophilized powder | Intravenous administration | Antihyperuricemic Agents, Gout suppressants | Uric acid |
1306 | Th1043 | Rasburicase | SAVKAARYGKDNVRVYKVHK Full view | 255 | Ic | Metabolic/Genetic | Fasturtec | N.A. | Powder and solvent that are made upto make solution. | Intravenous administartion | Antihyperuricemic Agents, Gout suppressants | Uric acid |
1324 | Th1045 | Imiglucerase | ARPCIPKSFGYSSVVCVCNA Full view | 255 | Ia | Metabolic | Cerezyme | Genzyme | Sterile, non-pyrogenic, white to off-white lyophilized product | Intravenous infusion | Enzyme Replacement Agents | Glucocerebroside |
1327 | Th1046 | Abciximab | H ReoPro-like antibo Full view | 218 | IIa | Genetic/Metabolic/Haemetological | ReoPro | Eli Lilly and Company | Clear, colorless, sterile, non-pyrogenic solution | Intravenous administartion | Platelet Aggregation Inhibitors, Anticoagulants | Integrin beta-3,Integrin alpha-IIb,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immuno |
1331 | Th1047 | Alpha-1-proteinase inhibitor | EDPQGDAAQKTDTSHHDQDH Full view | 255 | IIa | Metabolic/Geneti/Respiratory | Aralast | Baxter | Lyophilized powder | Intravenous infusion | Serine Proteinase Inhibitors, Enzyme replacement agents, trypsin inhibitors | Neutrophil elastase |
1332 | Th1047 | Alpha-1-proteinase inhibitor | EDPQGDAAQKTDTSHHDQDH Full view | 255 | IIa | Metabolic/Geneti/Respiratory | Prolastin | Talecris Biotherapeutics C formerly Bayer | Lyophilized powder | Intravenous infusion | Serine Proteinase Inhibitors, Enzyme replacement agents, trypsin inhibitors | Neutrophil elastase |
1358 | Th1050 | Pegademase bovine | MAQTPAFNKPKVELHVHLDG Full view | 255 | Ia | Metabolic | Adagen | Enzon Inc. | Isotonic, pyrogen free, sterile solution, pH 7.2-7.4 | Intramusular Injection | Enzyme Replacement Agents | Adenosine,Growth factor receptor-bound protein 2 |
1361 | Th1051 | Human Serum Albumin | MKWVTFISLLFLFSSAYSRG Full view | 609 | Ia | Hematological/Metabolic/genetic | Albuminar | CSL Behring | Sterile aqueous solution of albumin obtained from large pools of adult human venous plasma by low temperature controlled fractionation according to the Cohn process. | Albumin (Human) 25%, Albuminar-25 (albumin human) , is to be administered by the Intravenous route. | Serum substitutes | N.A. |
1362 | Th1051 | Human Serum Albumin | MKWVTFISLLFLFSSAYSRG Full view | 609 | Ia | Hematological/Metabolic/genetic | Albutein | GRIFOLS | Sterile, aqueous solution for single dose intravenous administration containing 20% human albumin (weight/volume). | Albutein 20% is to be administered by the Intravenous route. | Serum substitutes | N.A. |
1363 | Th1052 | Eptifibatide | Mpr-Har-Gly-Asp-Trp- Full view | 7 | Ib | Hematological/Metabolic | INTEGRILIN | Schering-Plough/Essex | Clear, colorless, sterile, non-pyrogenic solution of Eptifibatide | Injection Solution for IIntravenousUse | Platelet Aggregation Inhibitors | Lutropin-choriogonadotropic hormone receptor,Follicle-stimulating hormone receptor |
1382 | Th1060 | Insulin, porcine | A chain: GIVEQCCTSIC Full view | 51 | Ia | Hormonal/Metabolic | vetsulin | Intervet Inc (Merck Animal Health) | Sterile injectable suspension in multidose vials containing 10 mL of 40 IU/mL porcine insulin zinc suspension | Subcutaneous Injection | Hypoglycemic Agents | Interferon alpha/beta receptor 2,Interferon alpha/beta receptor 1, Hyaluronan, Transforming growth factor beta-1 |
1422 | Th1071 | Pancrelipase | Pancreatic alpha amy Full view | 1206 | Ia | Metabolic/genetic/ | Pancrecarb | Digestive care US, Inc. | Delayed-Release Capsules, Buffered and Enteric-Coated Microspheres. | Oral route | Gastrointestinal Agents and Enzyme Replacement Agents | Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch |
1423 | Th1071 | Pancrelipase | Pancreatic alpha amy Full view | 1206 | Ia | Metabolic/genetic/ | Viokace | Aptalis Pharma US, Inc. | Beige-white amorphous powder, miscible in water and practically insoluble in alcohol and converted to tablet form | Oral route | Gastrointestinal Agents and Enzyme Replacement Agents | Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch |
1424 | Th1071 | Pancrelipase | Pancreatic alpha amy Full view | 1206 | Ia | Metabolic/genetic/ | ULTRESA | Aptalis Pharma US, Inc. | Beige-white amorphous powder, miscible in water and practically insoluble or insoluble in alcohol and ether and converted to Delayed-Release Capsules | Oral route | Gastrointestinal Agents and Enzyme Replacement Agents | Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch |
1425 | Th1071 | Pancrelipase | Pancreatic alpha amy Full view | 1206 | Ia | Metabolic/genetic/ | PERTZYE | Digestive care US, Inc. | Beige-white amorphous powder, miscible in water and practically insoluble or insoluble in alcohol and ether PERTZYE delayed-release capsule | Oral route | Gastrointestinal Agents and Enzyme Replacement Agents | Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch |
1426 | Th1071 | Pancrelipase | Pancreatic alpha amy Full view | 1206 | Ia | Metabolic/genetic/ | ULTRASE | Axcan Pharma | Capsules Enteric-Coated Microspheres | Oral route | Gastrointestinal Agents and Enzyme Replacement Agents | Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch |
1427 | Th1071 | Pancrelipase | Pancreatic alpha amy Full view | 1206 | Ia | Metabolic/genetic/ | ZENPEP | Aptalis Pharma US, Inc. | Delayed-Release Capsules | Oral route | Gastrointestinal Agents and Enzyme Replacement Agents | Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch |
1428 | Th1072 | Streptokinase | MKNYLSFGMFALLFALTFGT Full view | 440 | Ic | Metabolic/Haemetological | Streptase | CSL Behring | Sterile, purified preparation formulated as lypholized powder | Intravenous and intracoronary administration. | Fibrinolytic Agents and Thrombolytic Agents | N.A. |
1434 | Th1074 | Alglucerase | ARPCIPKSFGYSSVVCVCNA Full view | 497 | Ia | Metabolic | Ceredase | Genzyme Corporation | Clear sterile non-pyrogenic solution of alglucerase in a citrate buffered solution | Intravenous injection | Enzyme Replacement Agents | Plasminogen,Proteinase-activated receptor 1 |
1437 | Th1076 | Laronidase | APHLVQVDAARALWPLRRFW Full view | 626 | Ia | Metabolic | ALDURAZYME | Genzyme Corporation | Sterile, nonpyrogenic, colorless to pale yellow, clear to slightly opalescent solution that must be diluted prior to administration in 0.9% Sodium Chloride Injection | Intravenous infusion | Enzyme Replacement Agents | N.A. |