A database of FDA approved therapeutic peptides and proteins
ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1029 | Th1005 | Etanercept | LPAQVAFTPYAPEPGSTCRL Full view | 255 | IIa | Immunological | Enbrel Sureclick | N.A. | Solution | Subcutaneous injection | Immunosuppressive Agents | Tumor necrosis factor,Tumor necrosis factor receptor superfamily member 1B,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c,Lymphotoxin-alpha,Low affinity immunoglobulin gamma Fc region re |
1033 | Th1006 | Bivalirudin | FPRPGGGGNGDFEEIPEEYL Full view | 20 | Ia | Hematological,Metabolic | Angiox | The Medicines Company UK Ltd | Powder for concentrate for solution | Injection | Antithrombins | Prothrombin |
1039 | Th1007 | Leuprolide | PHWSYLLR Full view | 8 | IIa | Cancer | Enantone | Takeda | Solution | Injection | Antineoplastic Agents, Hormonal and fertility agents, estrogen antagonists | Gonadotropin-releasing hormone receptor |
1049 | Th1008 | Peginterferon alfa-2a | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Pegasys | Hoffman-La Roche Inc | Sterile, preservative-free, colorless to light yellow injectable solution | Subcutaneous Injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1059 | Th1010 | Interferon alfa-n1 | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Infectious /Immunological | Wellferon | GlaxoSmithKline | Solution | Injection | Antiviral Agents, Immunologic factors, Immunosuppressiv agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1064 | Th1011 | Darbepoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Aranesp | Amgen Inc | Sterile, colorless, preservative-free solution containing polysorbate | Intravenousor Subcutaneous administration | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1071 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Binocrit | Sandoz | Clear colourless solution | Subcutaneous and Intravenous infusion | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1076 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Eprex | Janssen-Cilag. Ortho Biologics LLC | Solution | Subcutaneous and Intravenous infusion | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1077 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Nanokine | Nanogen Pharmaceutical biotechnology, Vietnam) | Sterile, white, lyophilized powder. The reconstituted preparation with 1 ml solvent (containing 0.9% benzyl alcohol) results in a clear, colorless solution. | Injection | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1078 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Procrit | Ortho Biotech | Sterile, colorless liquid in an isotonic sodium chloride/sodium citrate buffered solution or a sodium chloride/sodium phosphate buffered solution | Intravenous(IV) or Subcutaneous (SC) administration. | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1098 | Th1014 | Salmon Calcitonin | CSNLSTCVLGKLSQELHKLQ Full view | 32 | Ib | Osteological | Calcimar | N.A. | Solution | Subcutaneous or Intramuscular Injection | Bone Density Conservation Agents, Antihypercalcemic agents, Anti-osteoporotic agents | Calcitonin receptor |
1100 | Th1014 | Salmon Calcitonin | CSNLSTCVLGKLSQELHKLQ Full view | 32 | Ib | Osteological | Miacalcin | Novartis | Solution | Subcutaneous or Intramuscular Injection | Bone Density Conservation Agents, Antihypercalcemic agents, Anti-osteoporotic agents | Calcitonin receptor |
1110 | Th1015 | Interferon alfa-n3 | Alpha-2A:CDLPQTHSLG< Full view | 235 | Ib | Immunological | Alferon | Interferon Sciences Inc. | Solution | Injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1117 | Th1016 | Pegfilgrastim | MTPLGPASSLPQSFLLKCLE Full view | 175 | Ib | Immunological | Neulasta | Amgen Inc. | Solution | Subcutaneous injection | Immunosuppressive Agents, Anti-neutropenic agents | Granulocyte colony-stimulating factor receptor,Neutrophil elastase |
1120 | Th1017 | Sargramostim | APARSPSPSTQPWEHVNAIQ Full view | 127 | Ib | Immunological | Leucomax | Novartis | Solution | Subcutaneous and Intravenous infusion | Immunosuppressive Agents | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan |
1121 | Th1017 | Sargramostim | APARSPSPSTQPWEHVNAIQ Full view | 127 | Ib | Immunological | Leukine | Berlex Laboratories Inc | Sterile, preserved (1.1% benzyl alcohol), injectable solution (500 mcg/mL) and also as sterile, white, preservative free lyophilized powder (250 mcg) that requires reconstitution with 1 mL sterile water for Injection | Subcutaneous Injection (SC) or Intravenous infusion (IV) | Immunosuppressive Agents | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan |
1130 | Th1018 | Secretin | HSDGTFTSELSRLRDSARLQ Full view | 27 | IV | Hormonal disorders | Secremax | Repligen Corp | Solution | Intravenous | Diagnostic Agents | Secretin receptor |
1157 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Monoclate-P | N.A. | Lyophilized powder for solution | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1180 | Th1023 | Anakinra | MRPSGRKSSKMQAFRIWDVN Full view | 153 | IIa | Immunological | Kineret | Amgen Inc | Sterile, clear, colorless-to-white, preservative free solution | Subcutaneous (SC) administration | Immunosuppressive Agents, Anti-rheumatic agents | Interleukin-1 receptor type 1 |
1188 | Th1024 | Gramicidin D | VGALAVVVWLWLWLWX Full view | 16 | IIa | Infectious | Sofradex | Sanofi | Sterile, clear, bright, colourless, aqueous solution | Auricular and Ocular use. | Anti-Bacterial Agents, Anti-infective, Topical, Antibiotic | N.A. |
1195 | Th1025 | Intravenous Immunoglobulin | IGG1:PSALTQPPSASGSLG Full view | 250 | Ia | Immunological | Gamunex | Talecris Biotherapeutics | Sterile solution | Intravenous infusion | Immunosuppressive Agents, Immunologic factors, Anti-infective agents | High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg |
1205 | Th1027 | Insulin Regular | A-chain:GIVEQCCTSIC< Full view | 51 | Ia | Genetic/Hormonal | Humulin R | Eli Lilly and Company | Sterile, clear, aqueous, and colorless solution | Subcutaneous injection in the abdominal wall, the thigh, the gluteal region or in the upper arm and Intravenousadministration of Humulin R (insulin (human recombinant)) U-100 is possible under medical supervision. | Antidiabetic Agents | Insulin receptor,Insulin-like growth factor 1 receptor,Retinoblastoma-associated protein,Cathepsin D,Insulin-degrading enzyme,Neuroendocrine convertase 2,Carboxypeptidase E,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-r |
1206 | Th1027 | Insulin Regular | A-chain:GIVEQCCTSIC< Full view | 51 | Ia | Genetic/Hormonal | Novolin R | Novo Nordisk | Sterile, clear, aqueous, and colorless solution | Subcutaneous and Intravenous infusion | Antidiabetic Agents | Insulin receptor,Insulin-like growth factor 1 receptor,Retinoblastoma-associated protein,Cathepsin D,Insulin-degrading enzyme,Neuroendocrine convertase 2,Carboxypeptidase E,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-r |
1226 | Th1030 | Interferon gamma-1b | CYCQDPYVKEAENLKKYFNA Full view | 146 | Ib | Immunological | Actimmune | InterMune Inc | Sterile, clear, colorless solution | Subcutaneous Injection | Immunosuppressive Agents | Interferon gamma receptor 1,Interferon gamma receptor 2 |
1229 | Th1031 | Interferon Alfa-2a, Recombinant | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Roferon A | Hoffmann-La Roche Inc | Solution | Subcutaneous Injection | N.A. | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1260 | Th1037 | Botulinum Toxin Type B | MPVTINNFNYNDPIDNNNII Full view | 255 | Ic | Neurological Disorder | Myobloc | Solstice Neurosciences | Clear and colorless to light-yellow sterile injectable solution | Injection | Antidystonic Agents | Vesicle-associated membrane protein 2,Vesicle-associated membrane protein 1,Synaptotagmin-2 |
1261 | Th1037 | Botulinum Toxin Type B | MPVTINNFNYNDPIDNNNII Full view | 255 | Ic | Neurological Disorder | Neurobloc | Solstice Neurosciences | Clear and colourless to light yellow solution | Intramuscular Injection | Antidystonic Agents | Vesicle-associated membrane protein 2,Vesicle-associated membrane protein 1,Synaptotagmin-2 |
1269 | Th1039 | Lutropin alfa | Alpha Chain: APDVQDC Full view | 213 | Ib | Hormonal | Luveris | Serono | White lyophilised pellet withg clear colourless solvent to make solution | Subcutaneous (SC) administration | Fertility Agents | Lutropin-choriogonadotropic hormone receptor |
1275 | Th1040 | Insulin Lispro | A chain:GIVEQCCTSICS Full view | 51 | Ia | Hormonal/Metabolic/genetic | Humalog | Eli Lilly | Sterile, aqueous, clear, and colorless solution | Subcutaneous and Intravenous infusion | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1276 | Th1040 | Insulin Lispro | A chain:GIVEQCCTSICS Full view | 51 | Ia | Hormonal/Metabolic/genetic | Humalog KwikPen | Eli Lilly | Solution | Subcutaneous injection | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1283 | Th1041 | Insulin Glargine | A-chain:GIVEQCCTSICS Full view | 53 | Ia | Hormonal/Metabolic/genetic | Lantus | Sanofi-Aventis | Solution | Subcutaneous injection | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1284 | Th1041 | Insulin Glargine | A-chain:GIVEQCCTSICS Full view | 53 | Ia | Hormonal/Metabolic/genetic | Lantus OptiSet | N.A. | Solution | Subcutaneous injection | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1285 | Th1041 | Insulin Glargine | A-chain:GIVEQCCTSICS Full view | 53 | Ia | Hormonal/Metabolic/genetic | Lantus SoloStar | N.A. | Solution | Subcutaneous injection | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1306 | Th1043 | Rasburicase | SAVKAARYGKDNVRVYKVHK Full view | 255 | Ic | Metabolic/Genetic | Fasturtec | N.A. | Powder and solvent that are made upto make solution. | Intravenous administartion | Antihyperuricemic Agents, Gout suppressants | Uric acid |
1316 | Th1044 | Adalimumab | Light-chain:DIQMTQS< Full view | 230 | Ic | Immunological | Humira | Abbott Laboratories | Sterile, preservative-free solution | Subcutaneous administration | Immunosuppressive Agents, Anti-inflammatory, Antirheumatic agents | Tumor necrosis factor,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamm |
1317 | Th1044 | Adalimumab | Light-chain:DIQMTQS< Full view | 230 | Ic | Osteological | Humira Pen | Abbott Laboratories | Sterile, preservative-free solution | Subcutaneous injection | Immunosuppressive Agents, Anti-inflammatory, Antirheumatic agents | Tumor necrosis factor,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamm |
1327 | Th1046 | Abciximab | H ReoPro-like antibo Full view | 218 | IIa | Genetic/Metabolic/Haemetological | ReoPro | Eli Lilly and Company | Clear, colorless, sterile, non-pyrogenic solution | Intravenous administartion | Platelet Aggregation Inhibitors, Anticoagulants | Integrin beta-3,Integrin alpha-IIb,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immuno |
1337 | Th1048 | Pegaspargase | MEFFKKTALAALVMGFSGAA Full view | 255 | Ic | Cancer | Oncaspar | Enzon Inc | Solution | Intravenous or Intramuscular administration | Antineoplastic Agents | L-asparagine |
1342 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Betaferon | Bayer | Powder and solvent that are made upto make solution. | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1346 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Rebif | Merck | Sterile solution in a prefilled syringe or REBIF Rebidose autoinjector | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1358 | Th1050 | Pegademase bovine | MAQTPAFNKPKVELHVHLDG Full view | 255 | Ia | Metabolic | Adagen | Enzon Inc. | Isotonic, pyrogen free, sterile solution, pH 7.2-7.4 | Intramusular Injection | Enzyme Replacement Agents | Adenosine,Growth factor receptor-bound protein 2 |
1361 | Th1051 | Human Serum Albumin | MKWVTFISLLFLFSSAYSRG Full view | 609 | Ia | Hematological/Metabolic/genetic | Albuminar | CSL Behring | Sterile aqueous solution of albumin obtained from large pools of adult human venous plasma by low temperature controlled fractionation according to the Cohn process. | Albumin (Human) 25%, Albuminar-25 (albumin human) , is to be administered by the Intravenous route. | Serum substitutes | N.A. |
1362 | Th1051 | Human Serum Albumin | MKWVTFISLLFLFSSAYSRG Full view | 609 | Ia | Hematological/Metabolic/genetic | Albutein | GRIFOLS | Sterile, aqueous solution for single dose intravenous administration containing 20% human albumin (weight/volume). | Albutein 20% is to be administered by the Intravenous route. | Serum substitutes | N.A. |
1363 | Th1052 | Eptifibatide | Mpr-Har-Gly-Asp-Trp- Full view | 7 | Ib | Hematological/Metabolic | INTEGRILIN | Schering-Plough/Essex | Clear, colorless, sterile, non-pyrogenic solution of Eptifibatide | Injection Solution for IIntravenousUse | Platelet Aggregation Inhibitors | Lutropin-choriogonadotropic hormone receptor,Follicle-stimulating hormone receptor |
1365 | Th1053 | Serum albumin iodonated | MKWVTFISLLFLFSSAYSRG Full view | 600 | IV | Hematological Disorders | Megatope | IsoTex Diagnostics | Colorless to very pale yellow solutions | Injection for Intravenous administration | Diagnostic Agents | Apolipoprotein E,Serum amyloid A-1 protein,Protein AMBP |
1366 | Th1053 | Serum albumin iodonated | MKWVTFISLLFLFSSAYSRG Full view | 600 | IV | Hematological Disorders | Jeanotope | IsoTex Diagnostics | Sterile, nonpyrogenic, aqueos solution | Intravenous infusion | Diagnostic Agents | Apolipoprotein E,Serum amyloid A-1 protein,Protein AMBP |
1372 | Th1055 | Follitropin beta | A Chain: APDVQDCPECT Full view | 204 | Ib | Hormonal disorders | Follistim AQ | Merck | Sterile aqueous solution | Subcutaneous or Intramuscular administration | Fertility Agents | Follicle-stimulating hormone receptor |
1375 | Th1056 | Vasopressin | CYFQNCPRG Full view | 9 | Ib | Hormonal | Pitressin | JHP Pharmaceuticals | Sterile, aqueous solution of synthetic vasopressin | Intramuscular or Subcutaneous use | Antidiuretic Agents | Vasopressin V2 receptor,Vasopressin V1a receptor,Vasopressin V1b receptor |
1377 | Th1057 | Interferon beta-1b | MSYNLLGFLQRSSNFQSQKL Full view | 166 | Ib | Immunological | Betaferon | Bayer | Powder and solvent that are made upto make solution. | Subcutaneous Injection | Adjuvants, Immunologic and Immunosuppressive Agents | N.A. |
1381 | Th1059 | Hyaluronidase | MWTGLGPAVTLALVLVVAWA Full view | 476 | Ic | Adjunct Therapy | HYLENEX | Baxter Healthcare Corporation | Sterile, clear, colorless, nonpreserved, ready for use solution. | Human Injection Subcutaneous use | Adjuvants, Anesthesia and Permeabilizing Agents | N.A. |